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10.1093/jxb/erv066 56 MayerK.SchllerC.WambuttR.MurphyG.VolckaertG.PohlT.et al

IAA can scavenge free radicals, inhibit oxidative stress, and reduce the production of proinflammatory cytokines

We have shown that effective pharmacologic inhibition of GPX4 in PTC cells with direct inhibitor RSL3 induces a robust activation of ferroptosis, increased DNA damage, impaired DNA damage repair response due to reduced p-NPM1 levels, decreased cell viability and cell migration, as well as suppressed spheroid formation and viability in vitro

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