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However I came off Lymecycline in July & had my b12 shot and spots came back

Overall, the limited impact of NAC on mutational profiles suggests that chemotherapy exerts only modest selective pressure on tumor genomic architecture, and that genetic mutation dynamics alone are unlikely to be the primary drivers of recurrence in EC

Hypoxia Signaling in Human Health and Diseases: Implications and Prospects for Therapeutics

Endometriotic implants secrete estradiol (E2) as well as prostaglandin E2 (PGE2), agents that attract macrophages (monocyte chemotactic protein 1[MCP-1]), neurotrophic peptides (nerve growth factor [NGF]), enzymes for tissue remodeling (matrix metalloproteinases [MMPs]) and tissue inhibitors of MMPs (TIMPs), and proangiogenic substances such as vascular endothelial growth factor (VEGF) and interleukin-8 (6)