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Therefore, the notable efficacy of nAbs in established Ebola virus infection in monkeys and humans, even when symptoms are present, is perhaps a surprise, albeit an encouraging one for nAb therapies, given the severity and rapid spread of Ebola virus infection in vivo 157,158,159

This explains why researchers observe sustained benefits during the off-cycle period

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This study suggests that, on one side, expression of MET in CD8 + T cells may have a role in the causality of central nervous system pathology but, on the other side, HGF, through unknown mechanisms, may control this highly cytotoxic MET + CD8 + T-cell population