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Pharmacological therapeutics in Friedreich ataxia: the present state

B12 is essential for the formation of red blood cells, DNA synthesis, and the proper functioning of the nervous system

Briefly, mice exhibiting the FUSALS phenotype (characterized by FUS translocation from the nucleus to the cytoplasm) demonstrated longer lifespan, reduced disease severity and improved histological patterns when intracellular HSPA1A was overexpressed (Piavchenko et al., 2024

doi: 10.3390/life12122101 Summary Keywords interstitial lung disease, systemic sclerosis, cyclophosphamide, rituximab, mycophenolate mofetil, tocilizumab, nintedanib, pirfenidone Citation Kamenova A, Tzouvelekis A and Margaritopoulos GA (2023) Recent advances in the treatment of systemic sclerosis associated interstitial lung disease