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By integrating mechanistic insights with preclinical and emerging clinical evidence, we compared lipid-based, polymeric, vesicular, and dendritic nanocarriers, highlighting how particle size, surface chemistry, and ligand functionalization govern bloodbrain barrier transport and intracerebral distribution

[12] Furthermore, patients suffering from chronic diseases who require frequent dosing would greatly benefit from alternative administration routes

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Salidroside pretreatment alleviates ferroptosis induced by myocardial ischemia/reperfusion through mitochondrial superoxide-dependent AMPKalpha2 activation