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16 Therefore, U87-Luc was inoculated into the flanks of nude mice, and, after the tumor volume reached ~100 mm 3 , the animals were divided into eight groups and treated with phosphate-buffered saline (PBS), BSO, cisplatin, TMZ or combinations of these drugs

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o outro carrega efeitos colaterais que o tornam clinicamente inferior para a maioria das indicaes