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Indeed, on 18th September 2020, phase III study met its primary endpoint, showing that patients with COVID-19 associated pneumonia who received TCZ were 44% less likely to progress to mechanical ventilation or death compared to patients who received placebo

Meanwhile, the pH-sensitive polymer, abbreviated as N 3 -PEG 3.4k -PDHD with an azido terminal for subsequent DBCO-modified binding peptide coupling, was synthesized and confirmed by 1 H NMR and 19 F NMR spectra (Supplementary Figs

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