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The analysis also explores the therapeutic potential of targeting critical ferroptosis pathways, including dysregulated iron metabolism, impaired antioxidant defenses, and abnormal lipid peroxidation

Through this exploration, we aim to illuminate the broader implications of mTOR signaling in cellular function and disease and provide a comprehensive overview of current knowledge and future directions in studying transcriptome plasticity

We conducted a first cross-ancestry genomic study of PSMD in 58,403 participants from 24 population-based cohorts to decipher its genetic underpinnings