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Nicotinamide N-Methyltransferase Suppression Participates in Nickel-Induced Histone H3 Lysine9 Dimethylation in BEAS-2b Cells

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The immunoblot results revealed that CSD significantly depressed the phosphorylated Nrf2 (p-Nrf2) activation, and subsequently reduced the downstream anti-oxidative enzymes activities (i.e., SOD1 and GPx) (Figures 3A,C)