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Current Neuropharmacology, 19 (8), 12021224

The combination of reduced supportive cues and overactive VEGF-mediated signaling produces leaky, structurally abnormal microvessels that exacerbate BBB breakdown, microvascular degeneration, and neuronal vulnerability, highlighting astrocytes as critical modulators of neurovascular health and promising therapeutic targets in PD

The concentration of purified At LDOX was measured with a NanoDrop spectrophotometer (Thermo Fisher Scientific) at A 280nm using an extinction coefficient estimated with ProtParam 50