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A pertinent example of a non-P450 oxidative pathway is the alcohol dehydrogenase pathway that oxidizes alcohols to their aldehyde derivatives as part of the overall process of excretion

* Correspondence: Anis Ahmad, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Proc Natl Acad Sci U S A 116:2313223142

Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma