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For instance, articular chondrocytes in glycine-poor conditions produce significantly less collagen, and only when excess glycine is supplied does collagen synthesis increase substantially [123]

Your doctor can help you figure out the right treatment for you

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Sometimes people with metabolic acidosis will: Feel tired Not feel hungry (loss of appetite) Feel changes in heartbeat Have trouble thinking clearly Your healthcare provider should do a blood test to measure the level of acid in your blood before and during your treatment with Topiramate