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480 Spina bifida Spina bifida (the split spine in Latin) arises from pathological embryogenesis, in which the neural tube fails to close

Based on these observations, the first vaccination cycle was followed by a second prime-boost cycle 3 weeks later with 5 10 8 PFU of rMVA-EE2-MCP and 50 g of each antigen in the rEE2-rMCP-subunit boost vaccine, also 3 weeks apart

(24) investigated plasma mtDNA levels in RA patients and found that RA patients had a high sensitivity to mtDNA copy number compared to healthy controls, and also found that plasma mtDNA concentration was significantly correlated with the Disease Activity Score-28-Erythrocyte Sedimentation Rate (DAS28-ESR), which increased with the increase of DAS28-ESR, thus it is reasonable to believe that plasma mtDNA may be an inflammatory contributor as well as a biomarker in RA

Turato G, Di Stefano A, Maestrelli P, Mapp CE, Ruggieri MP, Roggeri A, et al