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This discrepancy may be due to AD-related injury at later disease stages, emphasizing the need for clinical trials initiated prior to dementia onset

Three days after doxycycline induction, 50 million cells per condition were treated with DMSO, rac -dHTC1 (10M) or SR-1114 (10M) for 8h in two biological replicates for ENL, and with DMSO, dHTC2 (2M) or dHTC3 (2M) for 16h in two biological replicates for BRD4s