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Palmitic acid treatment increases intracellular DAG and subsequently induces PKC-dependent Ser153 phosphorylation of Raf-kinase inhibitor protein (RKIP) that results in RKIP-Raf1 dissociation and activation of ERK signaling pathway [165]

Skin health and anti-aging: weak evidence Research on ALA for skin health is limited, with most findings coming from in vitro and animal studies.33 34 These suggest that ALAs antioxidant properties may help protect skin cells from UV damage, reduce inflammation, and support collagen integrity all key factors in skin aging

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