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Chronic oxidative stress and inflammation mediate the activation of multiple different downstream signaling pathways such as the NF-B, AP-1 and mammalian target of rapamycin (mTOR), Ras, and Wnt pathways, which are implicated in the development of major GI disorders such as gastric ulcer, ulcerative colitis, gastric cancer, and colorectal cancer [13,14,15,16]

Studies in different cancer models have shown that in vitro and in vivo experiments have reported the effects of FAO inhibitors on cancer inhibition

Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium

The slightly immunocompromised condition of G6PD-deficient patients may prevent severe inflammation, which may be consequently beneficial to patients