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As with other neurodegenerative diseases such as Alzheimers disease, Parkinsons disease, and Huntingtons disease, a significant number of fundamental studies have demonstrated that energy metabolism disorders resulting from mitochondrial dysfunction represent the primary pathophysiological phenotypes of amyotrophic lateral sclerosis (Sassani et al., 2020

If you are dosing GHK-Cu every 48 hours and miss a dose by 1224 hours, residual tissue-level activity from the prior dose is likely present but diminishing

The 5 mg dose produced 15% weight loss

Peer review Peer review information Nature Reviews Endocrinology thanks Thomas Lutz and the other, anonymous, reviewer(s) for their contribution to the peer review of this work