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Although the gut microbiota is well established in providing the host with protection against foreign pathogens, primarily by resisting intestinal colonisation by enteric pathogens, translocation of these microbes across the gut barrier can occur via various mechanisms and often results in undesirable outcomes for the host (Mainous et al

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Skin aging-dependent activation of the PI3K signaling pathway via downregulation of PTEN increases intracellular ROS in human dermal fibroblasts