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Wistar rats exhibited electrocardiographic (ECG) changes, enzyme alterations, and morphological lesions resembling acute myocardial infarction (AMI) type 8, suggesting a direct toxic effect of the venom on cardiac muscle, primarily attributed to melittin (62, 63)

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For example, mitochondrial dysfunction destabilizes lysosomes, amplifying oxidative stress ( 2.2.2 Endoplasmic reticulum: regulator of lipid metabolism and redox homeostasis The ER maintains cellular homeostasis through protein synthesis, lipid metabolism, and calcium storage ( - localized to the ER membranemediates cystine import for GSH synthesis (65)

S., Khandelwal, P