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It is a double-blind, placebo-controlled Phase 2 study enrolling 120 participants

reported a decreased incidence of G6PD-d in patients presenting to the hospital for coronary artery disease, though the sample size of G6PD-d patients was again limited and the case control design has more limitations when compared to retrospective cohort studies 17

While well-established in mice, the role of GPR43 in chicken Treg differentiation requires experimental confirmation using chicken-specific reagents

Impressions regarding the potential efficacy of glutamate-modulating agents therefore rest, for the present, on case series and open-label studies