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Zesiewicz, Theresa A.|Sullivan, Kelly L.|Hauser, Robert A

Epitalon is a laboratory-made peptide derived from epithalamin , a naturally occurring substance produced by the pineal gland

Conclusions In conclusion, based on the extensive knowledge accumulated over the last few decades related to the damaging oxidative pathways of free Hb and intraerythrocytic Hb (in health and in disease states), we can now fully explore these reactions in situations where RBCs are stored for a long duration, inactivated or even when derived from stem cells

Furthermore, it remains unknown whether increasing GPx1 expression in macrophages derived from patients with CD (either genetically or pharmacologically) would reduce their susceptibility to H 2 O 2 -induced cell death to levels comparable to that in healthy macrophages