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While clinical development for obesity was discontinued in 2007 after a Phase IIb trial failed to achieve its primary endpoint, the peptide remains a valuable research tool for investigating adipose tissue biology, lipolytic pathways, and receptor-independent signaling mechanisms

In the case of Tanzania, the acquisition of the SVMNT resistance haplotype was rapid (between 2003 and 2004), and it is unclear why we did not observe this haplotype in western Kenya