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Fazekas, A

Dose-response relationships between individual nonaspirin nonsteroidal anti-inflammatory drugs (NANSAIDs) and serious upper gastrointestinal bleeding: a meta-analysis based on individual patient data

doi: 10.1080/00325481.2021.2002616

There are four phases of first-in-human clinical trials, and the drug candidates are generally approved after the third phase if they are found safe and effective