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However, these approaches face inherent challenges: Neurons have limited regenerative capacity, are highly susceptible to metabolic stress, and require preservation of precise synaptic connectivity for proper network integration

While this concentration of IL-6 is significantly higher than what is reported in the CSF of control patients, this seemingly higher level of IL-6 is in line with concentrations reported from the CNS parenchyma taken from implanted microdialysis catheters (Woodroofe et al., 1991) and from post-mortem tissue (Li et al., 2009

Free Radic Res 49(9):11141121

Similarly, abundance of 15 fungal biomarkers was significantly elevated in gastric cancer patients compared to a control group