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Mecobalamin is also used in certain cases of anemia, nerve-related disorders, and as a supplement for individuals with vitamin B12 deficiency due to poor absorption or dietary insufficiency

Some individuals might only need injections once or twice a year

Given its primary metabolizing function, NNMT is predominantly expressed in the liver, but modest levels of the enzyme are also present in other tissues, including the adipose tissue, kidney, brain, lung, heart, and muscle