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It has numerous important roles in the body, such as improving resistance to stress, aiding digestion, promoting healthy skin, reducing muscle spasms, regulating blood pressure, and supporting energy production, detoxification, nerve transmission, blood formation, protein and fat synthesis, steroid hormone production, and blood sugar maintenance

A vial stored at room temperature for three weeks might look identical to one stored properly in the refrigerator, yet contain only 60 percent of the original active compound

In other words: Was the immune system in these children making an antibody that could prevent folate in the bloodstream from reaching the brain