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doi: 10.1073/pnas.2017364118 36 KankanamgeD.RatnayakeK.SamaradivakaraS.KarunarathneA

The density of these cells positively correlates with the severity of tau pathology, and their clustered aggregation is often a harbinger of neuritic plaque formation (149, 150)

Low glutathione levels can potentially cause increased fat storage and fatty liver disease

Indeed, a markedly increased SIRT7 expression was observed when EGF signaling activity was blocked in MDA-231 breast cancer cells by erlotinib, whereas EGF stimulation accelerated SIRT7 protein turnover (Fig