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These discrepancies could be problematic in clinical practice, affecting decision-making (Paterno et al., 2009) and patient safety

(2015) found a drop in GSH levels and Nernst potential (Eh) (indicating oxidative stress), an increase in 4-hydroxynonenal (4-HNE), and a decline in ovarian follicles in Gclm null female mice

Streptococcus pneumoniae extracellular vesicles aggravate alveolar epithelial barrier disruption via autophagic degradation of OCLN (Occludin)

An important early example investigated the effect of both knockout and transgenic uricase in mice receiving intracerebral 6-hydroxydopamine administration, which leads to dopaminergic neurodegeneration 33